| Description |
1 online resource (xix, 526 pages). |
| Physical Medium |
polychrome |
| Description |
text file |
| Series |
New developments in mass spectrometry ; 11
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New developments in mass spectrometry ; 11.
|
| Summary |
Over the last decade, the use of ion mobility separation in combination with mass spectrometry analysis has developed significantly. This technique adds a unique extra dimension enabling the in-depth analysis of a wide range of complex samples in the areas of the chemical and biological sciences. Providing a comprehensive guide to the technique, each chapter is written by an internationally recognised expert and with numerous different commercial platforms to choose from, this book will help the end users understand the practicalities of using different instruments for different ion mobility purposes. The first section provides a detailed account of the fundamentals behind the technique and the current range of available instrumentation. The second section focusses on the wide range of applications that have benefitted from ion mobility - mass spectrometry and includes topics taken from current research in the pharmaceutical, metabolomics, glycomics, and structural molecular biology fields. The book is primarily aimed at researchers, appealing to practising chemists and biochemists, as well as those in the pharmaceutical and medical fields. |
| Bibliography |
Includes bibliographical references and index. |
| Contents |
Ion mobility-mass spectrometry: an overview / Valérie Gabelica -- Calculation of momentum transfer cross-sections / C. Bleiholder, F.C. Liu and M. Chai -- Fundamentals of uniform-field drift tube ion mobility and collision cross section / S. M. Stow and J. C. Fjeldsted -- Travelling wave ion mobility separation: basics and calibration / K. Richardson and K. Giles -- Trapped ion mobility spectrometry: basics and calibration / M. Ridgeway, L. Woods and M. Park -- Field asymmetric ion mobility spectrometry (FAIMS) for advanced mass spectrometry / M. Belford, S. Prasad, S. Peterman, E. Bonneil, J. Lanoix, C. Durette, P. Thibault, K. MOtamedchaboki, R. Huguet, D. Lopez-Ferrer, R. D. Melani, K. Srzentić, L. Fornelli, N. L. Kelleher, R. W. Purves, K. Walker, Y. Zhu, G. de Albuquerque Cavalcanti, N. Wijeratne and C. Boeser -- Computational approaches for processing native ion mobility-mass spectrometry data / T. Cragnolini and K. Thalassinos -- CCS for modeling 3D structures / E. G. Marklund, M. T. Degiacomi, A. Politis and M. Landreh -- Ion spectroscopy coupled to ion mobility-mass spectrometry / Iuliia Stroganova and Anouk M. Rijs -- Ion mobility-mass spectrometry of pharmaceuticals / Andrew D. Ray, Anthony W. T. Bristow and Stephen W. Holman -- Ion mobility spectrometry in mass spectrometry imaging / Oliver J. Hale, Eva Illes-Toth, Emma K. Sisley and Helen J. Cooper -- Ion mobility-mass spectrometry in metabolomics studies / Emanuel Zlibut, Katrina L. Leaptrot, Jody C. May and John A. McLean -- The role of ion mobility for antibody characterisation: a biopharmaceutical perspective / Iain D. G. Campuzano -- Insights into membrane protein structure and function by means of ion mobility-mass spectrometry / Anna J. Higgins and Antonio N. Calabrese -- Conformational characterisation of biomolecules / Ruth Knox, Alexey Barkhanskiy, Aidan P. France and Perdita E. Barran -- Advanced IM-MS-based approaches for protein analysis: collision-induced unfolding (CIU) and hypenation of liquid chromatography to IM-MS / E. Deslignière, O. Hernandez-Alba and S. Cianférani -- Ion mobility-mass spectrometry of nucleic acids / Dan Fabris -- Glycomics and ion mobility / W. B. Struwe |
| Local Note |
eBooks on EBSCOhost EBSCO eBook Subscription Academic Collection - North America |
| Subject |
Ion mobility spectroscopy.
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Ion mobility spectroscopy. |
| Added Author |
Ashcroft, Alison E., editor.
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Sobott, Frank, editor.
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| Other Form: |
Print version: ION MOBILITY-MASS SPECTROMETRY. 9781839161667 1839161663 (OCoLC)1223071927 |
| ISBN |
9781839162886 (electronic book) |
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1839162880 (electronic book) |
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9781839162893 (electronic book) |
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1839162899 (electronic book) |
|
9781839161667 |
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1839161663 |
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