| Description |
1 online resource (xxiii, 209 pages) : illustrations (some color). |
| Physical Medium |
polychrome |
| Description |
text file |
| Series |
The practical approach series ; 200
|
|
Practical approach series ; 200.
|
| Bibliography |
Includes bibliographical references and index. |
| Access |
Use copy Restrictions unspecified MiAaHDL |
| Summary |
The DNA of eukaryotes is packaged into chromosomes - each chromosome consisting of a very long molecule of DNA and various proteins (for example, histones), and the number of chromosomes being characteristic for the species concerned. Chromosome analysis can provide a great deal of information for many aspects of cellular genetics such as DNA replication, The book is structured in a methodical fashion - the introductory chapters are centred around analysis of chromatin with chapters on the mapping of protein: DNA interactions "in vivo" using ligation-mediated PCR and the mapping of chromatin-associated proteins by formaldehyde cross-linking. The next chapters concentrate on the study of whole chromosome structure, including: fission yeast chromosome analysis using FISH and CHIP, isolation of vertebrate metaphase chromosomes and their analysis by FISH, the study of vertebrate chromosome progression through mitosis, and the analysis of mammalian interphase chromosomes by immunofluorescence and FISH. There then follow chapters on FISH in whole-mount tissues and the analysis of the sub-structure of mammalian nuclei "in vitro." |
| Reproduction |
Electronic reproduction. [S.l.] : HathiTrust Digital Library, 2010. MiAaHDL |
| System Details |
Master and use copy. Digital master created according to Benchmark for Faithful Digital Reproductions of Monographs and Serials, Version 1. Digital Library Federation, December 2002. http://purl.oclc.org/DLF/benchrepro0212 MiAaHDL |
| Processing Action |
digitized 2010 HathiTrust Digital Library committed to preserve MiAaHDL |
| Local Note |
eBooks on EBSCOhost EBSCO eBook Subscription Academic Collection - North America |
| Subject |
Chromosomes -- Laboratory manuals.
|
|
Chromosomes. |
| Genre/Form |
Laboratory manuals.
|
| Subject |
Genetics -- Laboratory manuals.
|
|
Genetics. |
|
Chromosomes. |
| Genre/Form |
Laboratory Manual.
|
|
Electronic books.
|
| Subject |
Chromosomes. |
| Genre/Form |
Laboratory manuals.
|
| Added Author |
Bickmore, Wendy.
|
| Other Form: |
Print version: Chromosome structural analysis. Oxford ; New York : Oxford University Press, 1999 0199636990 0199636982 (DLC) 98046718 (OCoLC)40061359 |
| ISBN |
0585484090 (electronic book) |
|
9780585484099 (electronic book) |
|
1280375590 |
|
9781280375590 |
|
0199636990 (hardback) |
|
9780199636990 (hardback) |
|
0199636982 (paperback) |
|
9780199636983 (paperback) |
|
