| Description |
1 online resource. |
|
text file PDF |
| Physical Medium |
polychrome |
| Series |
RSC drug discovery ; no. 39
|
|
RSC drug discovery series ; 39.
|
| Note |
Includes index. |
| Bibliography |
Includes bibliographical references and index. |
| Contents |
Ion channel drug discovery: a historical perspective / Brian Cox -- High-throughput screening / Alexander Böcker, Sabine Schaertl and Stephen D. Hess -- Automated electrophysiology in ion channel drug discovery / John Dunlop -- Structural understanding of ion channels in atomic detail / Phillip J. Stansfeld -- Voltage-gated sodium channels: structure, function, and molecular pharmacology / William A. Catterall -- AMPA receptor positive allosteric modulators: a case history / Simon E Ward -- The discovery of novel inhaled ENaC blockers for the treatment of cystic fibrosis lung disease / Catherine Howsham and Henry Danahay -- The therapeutic potential of small-molecule modulators of the cystic fibrosis transmembrane conductance regulator (CFTR) Cl-channel / Jia Liu, Gerta Cami-Kobeci, Yiting Wang, Pissared Khuituan, Zhiwei Cai, Hongyu Li, Stephen M. Husbands and David N. Sheppard -- TRPV1 antagonism: from research to clinic / Mark S. Nash, J. Martin Verkuyl and Gurdip Bhalay -- Open access to the KCNQ channel: retigabine and second generation M-current openers / Johannes Krupp, Anthony M. Rush, Britt-Marie Swahn and Martin Main -- The therapeutic potential of hERG1 K+ channels for treating cancer and cardiac arrhythmias / John Mitcheson and Annarosa Arcangeli -- Does nature do ion channel drug discovery better than us? / Richard J. Lewis, Irina Vetter, Fernanda C. Cardoso, Marco Inserra and Glenn King -- Antibodies as ion channel modulators / Wilson Edwards and Alan D. Wickenden -- Ion channel drug discovery: future perspectives / Martin Gosling. |
| Local Note |
eBooks on EBSCOhost EBSCO eBook Subscription Academic Collection - North America |
| Subject |
Pharmaceutical chemistry.
|
|
Pharmaceutical chemistry. |
|
Drug development.
|
|
Drug development. |
|
Ion channels.
|
|
Ion channels. |
|
Ion Channels. |
|
Drug Discovery -- methods. |
| Genre/Form |
Electronic books.
|
| Added Author |
Cox, Brian (Chemist), contributing editor.
|
|
Gosling, Martin, contributing editor.
|
| Other Form: |
Electronic reproduction of (manifestation): Ion channel drug discovery. Cambridge : Royal Society of Chemistry, 2012 9781849731867 (OCoLC)808499240 |
| ISBN |
9781849735087 (e-book) |
|
1849735085 (e-book) |
|
9781782623076 (e-book) |
|
1782623078 (e-book) |
|
9781849731867 (print) |
|
1849731861 (print) |
|
