| Description |
1 online resource (368 pages). |
| Physical Medium |
polychrome |
| Description |
text file |
| Series |
RSC detection science series ; 11
|
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RSC detection science series ; no. 11.
|
| Note |
Includes index. |
|
Title from title details screen. |
| Contents |
Front Cover; Quenched-phosphorescence Detection of Molecular Oxygen: Applications in Life Sciences; Preface; Contents; Chapter 1 -- Fundamentals of Quenched Phosphorescence O2 Sensing and Rational Design of Sensor Materials; 1.1 Introduction; 1.2 Mechanism of Oxygen Quenching; 1.3 Requirements for Phosphorescent Indicators; 1.4 Brief Overview of the Most Common Indicators; 1.5 Rational Design of Optical Sensing Materials; 1.6 Sensitivity and Dynamic Range of Oxygen Sensors; 1.7 Referenced Oxygen Sensing and Imaging; 1.8 Artefacts in Oxygen Sensing; 1.9 Conclusions and Outlook; References |
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Chapter 2 -- New Polymer-based Sensor Materials and Fabrication Technologies for Large-scale Applications2.1 Introduction; 2.2 Physical Entrapment of Phosphors Within Inorganic and Organic Matrices; 2.2.1 Casting of Polymer 'Cocktails'; 2.2.2 Physical Mixing of Phosphors with Ormosils; 2.2.3 Phosphor Integration in Silicone Rubbers; 2.2.4 Impregnation of Microporous Membranes and Microparticles with Phosphor Molecules; 2.2.5 Solvent Crazing; 2.2.6 Electrospinning; 2.2.7 Electrophoretic Deposition; 2.2.8 Layer-by-layer Deposition (LbL) |
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2.3 Covalent and Coordinative Binding of Phosphors to Substrates2.4 Conclusions and Outlook; Abbreviations; Acknowledgement; References; Chapter 3 -- Evolution of Cell-penetrating Phosphorescent O2 Probes; 3.1 Evolution of Cell-penetrating Phosphorescent O2 probes; 3.1.1 Introduction; 3.1.2 Why and How to Measure Intracellular O2; 3.1.3 Different Classes of Cell-penetrating O2 Probes and Their Evolution; 3.1.3.1 Small Molecule Probes and Other Conjugates; 3.1.3.2 Nanoparticles of First Generation; 3.1.3.3 Nanoparticles of Second Generation; 3.1.3.4 Nanoparticles of Third Generation |
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3.2 Conclusions and Future OutlookAcknowledgement; References; Chapter 4 -- Hydrophilic Ir(iii) Complexes for In vitro and In vivo Oxygen Imaging; 4.1 Introduction; 4.2 Experimental; 4.2.1 Synthesis of BTP-PEGn (n = 12, 24, 48) and PPY-PEG24; 4.2.2 Photophysical Properties in Aqueous Solutions; 4.2.3 Octanol/Water Partition Coefficients (logPO/W); 4.2.4 Fluorescence and Phosphorescence Lifetime Imaging Microscopy; 4.2.5 Cell Culture and Imaging; 4.2.6 In vivo Imaging; 4.3 Results and Discussion; 4.3.1 Electronic Structures of the Ir(iii) Complexes |
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4.3.2 Hydrophilicity and Photophysical Properties in Water4.3.3 Phosphorescence Quenching by Molecular Oxygen in Solution; 4.3.4 Temperature Effects on Phosphorescence Quenching by O2; 4.3.5 Cellular Uptake and Oxygen Response; 4.3.6 In vivo O2 Imaging by PLIM Measurements; 4.4 Conclusion; Acknowledgement; References; Chapter 5 -- Protection of Triplet Excited State Materials from Oxygen Quenching and Photooxidation in Optical Sensing Applications; 5.1 Introduction; 5.2 Phosphorescent Probes with Appended Protective Groups; 5.2.1 Phosphorescent Dendrimers |
| Summary |
Significant progress has been made in recent years in quenched-phosphorescence oxygen sensing, prompted by this the editors have delivered a dedicated book that brings together these developments, provides a comprehensive overview of the different detection methodologies, and representative examples and applications. |
| Local Note |
eBooks on EBSCOhost EBSCO eBook Subscription Academic Collection - North America |
| Subject |
Chemical detectors.
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Chemical detectors. |
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Oxygen.
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Oxygen. |
| Genre/Form |
Electronic books.
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| Added Author |
Papkovsky, Dmitri B., editor.
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Dmitriev, Ruslan I., editor.
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| ISBN |
9781788013451 (electronic book) |
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178801345X (electronic book) |
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9781788011754 (print) |
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1788011759 (print) |
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