Description |
1 online resource. |
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text file PDF |
Physical Medium |
polychrome |
Series |
RSC drug discovery ; no. 39
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RSC drug discovery series ; 39.
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Note |
Includes index. |
Bibliography |
Includes bibliographical references and index. |
Contents |
Ion channel drug discovery: a historical perspective / Brian Cox -- High-throughput screening / Alexander Böcker, Sabine Schaertl and Stephen D. Hess -- Automated electrophysiology in ion channel drug discovery / John Dunlop -- Structural understanding of ion channels in atomic detail / Phillip J. Stansfeld -- Voltage-gated sodium channels: structure, function, and molecular pharmacology / William A. Catterall -- AMPA receptor positive allosteric modulators: a case history / Simon E Ward -- The discovery of novel inhaled ENaC blockers for the treatment of cystic fibrosis lung disease / Catherine Howsham and Henry Danahay -- The therapeutic potential of small-molecule modulators of the cystic fibrosis transmembrane conductance regulator (CFTR) Cl-channel / Jia Liu, Gerta Cami-Kobeci, Yiting Wang, Pissared Khuituan, Zhiwei Cai, Hongyu Li, Stephen M. Husbands and David N. Sheppard -- TRPV1 antagonism: from research to clinic / Mark S. Nash, J. Martin Verkuyl and Gurdip Bhalay -- Open access to the KCNQ channel: retigabine and second generation M-current openers / Johannes Krupp, Anthony M. Rush, Britt-Marie Swahn and Martin Main -- The therapeutic potential of hERG1 K+ channels for treating cancer and cardiac arrhythmias / John Mitcheson and Annarosa Arcangeli -- Does nature do ion channel drug discovery better than us? / Richard J. Lewis, Irina Vetter, Fernanda C. Cardoso, Marco Inserra and Glenn King -- Antibodies as ion channel modulators / Wilson Edwards and Alan D. Wickenden -- Ion channel drug discovery: future perspectives / Martin Gosling. |
Local Note |
eBooks on EBSCOhost EBSCO eBook Subscription Academic Collection - North America |
Subject |
Pharmaceutical chemistry.
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Pharmaceutical chemistry. |
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Drug development.
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Drug development. |
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Ion channels.
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Ion channels. |
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Ion Channels. |
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Drug Discovery -- methods. |
Genre/Form |
Electronic books.
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Added Author |
Cox, Brian (Chemist), contributing editor.
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Gosling, Martin, contributing editor.
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Other Form: |
Electronic reproduction of (manifestation): Ion channel drug discovery. Cambridge : Royal Society of Chemistry, 2012 9781849731867 (OCoLC)808499240 |
ISBN |
9781849735087 (e-book) |
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1849735085 (e-book) |
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9781782623076 (e-book) |
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1782623078 (e-book) |
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9781849731867 (print) |
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1849731861 (print) |
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