LEADER 00000cam a2200793Ii 4500 001 on1137040539 003 OCoLC 005 20210702122909.7 006 m o d 007 cr cnu|||unuuu 008 200120t20202020enk ob 001 0 eng d 015 GBC014741|2bnb 016 7 019685296|2Uk 019 1137751764 020 9781839160455|q(electronic book) 020 1839160454|q(electronic book) 020 9781839161353|q(electronic book) 020 1839161353|q(electronic book) 020 |z9781788017220 020 |z1788017226 035 (OCoLC)1137040539|z(OCoLC)1137751764 037 3-178-9781839161353|bIngram Content Group 040 N$T|beng|erda|epn|cN$T|dN$T|dUKRSC|dEBLCP|dYDX|dOCLCF |dUKMGB|dUIU|dUKAHL|dOCLCQ 049 RIDW 050 4 QH582 072 7 SCI|x017000|2bisacsh 072 7 SCI|x013010|2bisacsh 072 7 PNF|2bicssc 072 7 PSF|2bicssc 082 04 571.6|223 090 QH582 100 1 Ju, Huangxian,|0https://id.loc.gov/authorities/names/ n2008181119|eauthor. 245 10 In situ analysis of cellular functional molecules / |cHuangxian Ju, Bo Tang, Lin Ding. 264 1 Cambridge :|bRoyal Society of Chemistry,|c[2020] 264 4 |c©2020 300 1 online resource. 336 text|btxt|2rdacontent 337 computer|bc|2rdamedia 338 online resource|bcr|2rdacarrier 340 |gpolychrome|2rdacc 347 text file|2rdaft 490 1 Detection science series ;|vno. 16 504 Includes bibliographical references and index. 505 0 Intro -- Title -- Copyright -- Preface -- Contents -- Chapter 1 Design of In Situ Cytosensing Strategies -- 1.1 General Principles of In Situ Cytosensing -- 1.2 Enhancement of Detection Specificity -- 1.3 Design of Off- On Signal Switch -- 1.4 Design of Signal Amplification Strategy -- 1.5 Design of Multi-channel Analysis -- 1.6 Perspective -- References -- Chapter 2 In Situ Detection of Cell-surface Glycans -- 2.1 Introduction to Cell- surface Glycans -- 2.1.1 Structures and Classification of Glycans -- 2.1.2 Functions of Glycans -- 2.2 Labelling and Recognition of Glycans 505 8 2.2.1 Lectin Recognition -- 2.2.2 Chemoselective Labelling -- 2.2.3 Metabolic Oligosaccharide Engineering -- 2.2.4 Chemoenzymatic Glycan Labelling -- 2.3 Global Analysis of Cell-surface Glycans -- 2.4 Competition Systems for Quantification of Cell-surface Glycans -- 2.5 Protein- specific Imaging of Cell-surface glycans -- 2.6 Perspective -- References -- Chapter 3 In Situ Detection of Intracellular Messenger RNA and MicroRNA -- 3.1 Introduction -- 3.2 Biofunction of mRNA and miRNA -- 3.2.1 Biofunction of mRNA -- 3.2.2 Biofunction of miRNA -- 3.3 Viral Gene Vectors 505 8 3.3.1 Lenti-/Retrovirus-mediated Vectors for Gene Delivery -- 3.3.2 Adenovirus-mediated Vectors for Gene Delivery -- 3.3.3 Adeno-associated Virus Vectors for Gene Delivery -- 3.4 Organic Gene Vectors -- 3.4.1 Cationic Polymers -- 3.4.2 Cationic Lipids -- 3.5 Inorganic Gene Vectors -- 3.5.1 Gold-based Nanomaterials as Gene Vectors -- 3.5.2 Two-dimensional GO and TMD Nanosheets as Gene Vectors -- 3.6 Intracellular mRNA Detection -- 3.7 Intracellular miRNA Detection -- 3.7.1 "One-to-One" Signal Detection -- 3.7.2 Sensitive Detection Based on Signal Amplification -- 3.8 Perspective and Challenges 505 8 Acknowledgements -- References -- Chapter 4 In Situ Analysis of Intracellular Telomerase Activity -- 4.1 Clinical Significance of Telomerase -- 4.2 Traditional Analytical Methods for Telomerase -- 4.3 In Situ Imaging of Intracellular Telomerase Activity Based on Functional Nanoprobes -- 4.4 In Situ Imaging of Intracellular Telomerase Activity Through FRET -- 4.4.1 FRET Based on Organic Quenchers -- 4.4.2 FRET Based on AuNPs -- 4.5 Raman Spectroscopy-based Intracellular Telomerase Activity Sensing -- 4.6 In Situ Monitoring of Intracellular Telomerase Activity Using AIEgen-based Bioprobes 505 8 4.7 Perspective -- Acknowledgements -- References -- Chapter 5 In Situ Analysis of the Intracellular Caspase Family -- 5.1 Introduction to the Intracellular Caspase Family -- 5.2 Imaging of Caspase Activity in Living Cells -- 5.2.1 FRET-based Sensors for Imaging of Intracellular Caspase Activity -- 5.2.2 Fluorescence Lifetime Imaging Microscopy for Imaging of Intracellular Caspase Activity - - 5.2.3 AIE Probe for Imaging of Intracellular Caspase Activity -- 5.2.4 Two-photon (TP) Imaging of Intracellular Caspase Activity 520 This book introduces the tailor-made design of detection probes as well as schemes from a top-down perspective according to the unique characteristics of cellular functional molecules. 588 0 Online resource; title from PDF title page (EBSCO, viewed January 21, 2020). 590 eBooks on EBSCOhost|bEBSCO eBook Subscription Academic Collection - North America 650 0 Cytology|0https://id.loc.gov/authorities/subjects/ sh85035240|xAnalysis.|0https://id.loc.gov/authorities/ subjects/sh2002006221 650 0 Molecular biology.|0https://id.loc.gov/authorities/ subjects/sh85086577 650 0 Molecules.|0https://id.loc.gov/authorities/subjects/ sh85086597 650 7 Cytology.|2fast|0https://id.worldcat.org/fast/886282 650 7 Molecular biology.|2fast|0https://id.worldcat.org/fast/ 1024734 650 7 Molecules.|2fast|0https://id.worldcat.org/fast/1024869 655 4 Electronic books. 700 1 Tang, Bo,|d1964-11-|0https://id.loc.gov/authorities/names/ n2021181378|eauthor. 700 1 Ding, Lin,|d1981-|0https://id.loc.gov/authorities/names/ n2021181379|eauthor. 776 08 |iPrint version:|z1788017226|z9781788017220 |w(OCoLC)1110449873 830 0 RSC detection science series ;|0https://id.loc.gov/ authorities/names/no2014003495|vno. 16. 856 40 |uhttps://rider.idm.oclc.org/login?url=https:// search.ebscohost.com/login.aspx?direct=true&scope=site& db=nlebk&AN=2356575|zOnline ebook via EBSCO. Access restricted to current Rider University students, faculty, and staff. 856 42 |3Instructions for reading/downloading the EBSCO version of this ebook|uhttp://guides.rider.edu/ebooks/ebsco 901 MARCIVE 20231220 948 |d20210708|cEBSCO|tEBSCOebooksacademic NEW 5016 |lridw 994 92|bRID