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Title Binding, transport and storage of metal ions in biological cells / edited by Wolfgang Maret and Anthony Wedd.

Publication Info. Cambridge, UK : Royal Society of Chemistry, [2014]

Item Status

Description 1 online resource (xxv, 911 pages) : illustrations (some color).
text file PDF
Physical Medium polychrome
Series RSC metallobiology series, 2045-547X ; 2
RSC metallobiology series ; 2.
Summary Metal ions play key roles in biology. Many are essential for catalysis, for electron transfer and for the fixation, sensing, and metabolism of gases. Others compete with those essential metal ions or have toxic or pharmacological effects. This book is structured around the periodic table and focuses on the control of metal ions in cells. It addresses the molecular aspects of binding, transport and storage that ensure balanced levels of the essential elements. Organisms have also developed mechanisms to deal with the non-essential metal ions. However, through new uses and manufacturing processes, organisms are increasingly exposed to changing levels of both essential and non-essential ions in new chemical forms. They may not have developed defenses against some of these forms (such as nanoparticles). Many diseases such as cancer, diabetes and neurodegeneration are associated with metal ion imbalance. There may be a deficiency of the essential metals, overload of either essential or non-essential metals or perturbation of the overall natural balance. This book is the first to comprehensively survey the molecular nature of the overall natural balance of metal ions in nutrition, toxicology and pharmacology. It is written as an introduction to research for students and researchers in academia and industry and begins with a chapter by Professor R J P Williams FRS.
Bibliography Includes bibliographical references and index.
Local Note eBooks on EBSCOhost EBSCO eBook Subscription Academic Collection - North America
Subject Metals in the body.
Metals in the body.
Cell physiology.
Cell physiology.
Metal ions.
Metal ions.
Genre/Form Electronic books.
Added Author Maret, W. (Wolfgang), editor.
Wedd, Anthony, editor.
Other Form: Print version: Binding, transport and storage of metal ions in biological cells 1849735999 (OCoLC)864278867
ISBN 9781849739979 (electronic book)
1849739978 (electronic book)
9781782622826 (electronic book)
1782622829 (electronic book)
1849735999
9781849735995