LEADER 00000cam a2200601Ia 4500 
001    ocn824353600 
003    OCoLC 
005    20160527040552.9 
006    m     o  d         
007    cr |n||||||||| 
008    130114s2012    enka    ob    001 0 eng d 
020    1849734933|q(electronic book) 
020    9781849734936|q(electronic book) 
020    |z9781849734271|q(hardback) 
020    |z1849734275|q(hardback) 
024 7  10.1039/9781849734936|2doi 
035    (OCoLC)824353600 
040    YDXCP|beng|epn|cYDXCP|dOCLCO|dUKRSC|dUIU|dMYG|dN$T|dIUL
       |dOCLCF|dNJR|dOCLCQ|dDEBSZ|dOCLCQ 
049    RIDW 
050  4 QP624|b.D63 2012eb 
072  7 SCI|x029000|2bisacsh 
082 04 572.8/645|223 
090    QP624|b.D63 2012eb 
245 00 DNA conjugates and sensors /|cedited by Keith R. Fox, Tom 
       Brown. 
264  1 Cambridge, U.K. :|bRSC Pub.,|c[2012] 
264  4 |c©2012 
300    1 online resource (xii, 303 pages) :|billustrations (some 
       color). 
336    text|btxt|2rdacontent 
337    computer|bc|2rdamedia 
338    online resource|bcr|2rdacarrier 
347    text file|2rdaft 
490 1  RSC biomolecular sciences,|x1757-7152 ;|vno. 26 
504    Includes bibliographical references and index. 
520    "Applications of nucleic acids have developed recently to 
       provide solutions for biosensors, diagnostic tools and as 
       platforms for the assembly of complex structures. These 
       developments have been possible as their base sequence can
       be used to assemble precise structures following simple 
       and predictable rules. Self-assembled DNA can then be 
       amplified using polymerase chain reaction (PCR) and this 
       ultimately enables the preparation of synthetic nucleic 
       acids. Their use as molecular tools or DNA-conjugates has 
       recently been enhanced by the addition of other groups 
       including enzymes, fluorophores and small molecules. 
       Written by leaders in the field, this volume describes the
       preparation and application of these DNA-conjugates. 
       Several have been used as sensors (aptamers, riboswitches 
       and nanostructures) based on the ability of nucleic acids 
       to adopt specific structures in the presence of ligands, 
       whilst others link reporter groups such as proteins or 
       fluorophores to RNA or DNA for detection, single molecule 
       studies, and increasing the sensitivity of PCR. The book 
       will interest researchers in areas related to analytical 
       chemistry, chemical biology, medicinal chemistry, 
       molecular pharmacology, and structural and molecular 
       biology."--|cProvided by publisher. 
588 0  Print version record. 
590    eBooks on EBSCOhost|bEBSCO eBook Subscription Academic 
       Collection - North America 
650  0 DNA|xSynthesis.|0https://id.loc.gov/authorities/subjects/
       sh85037010 
650  7 DNA|xSynthesis.|2fast|0https://id.worldcat.org/fast/886578
650 12 DNA|xbiosynthesis.|0https://id.nlm.nih.gov/mesh/
       D004247Q000096 
650 22 Aptamers, Nucleotide|xbiosynthesis.|0https://
       id.nlm.nih.gov/mesh/D052157Q000096 
650 22 Biosensing Techniques.|0https://id.nlm.nih.gov/mesh/
       D015374 
655  0 Electronic books. 
700 1  Fox, Keith R.|0https://id.loc.gov/authorities/names/
       nb97033639 
700 1  Brown, Tom|c(Biochemist)|0https://id.loc.gov/authorities/
       names/nb2012030002 
776 08 |iPrint version:|tDNA conjugates and sensors.|dCambridge :
       RSC Publishing, ©2012|z9781849734271|w(OCoLC)821679580 
830  0 RSC biomolecular sciences ;|0https://id.loc.gov/
       authorities/names/n2006182099|v26. 
856 40 |uhttps://rider.idm.oclc.org/login?url=http://
       search.ebscohost.com/login.aspx?direct=true&scope=site&
       db=nlebk&AN=519375|zOnline eBook. Access restricted to 
       current Rider University students, faculty, and staff. 
856 42 |3Instructions for reading/downloading this eBook|uhttp://
       guides.rider.edu/ebooks/ebsco 
901    MARCIVE 20231220 
948    |d20160607|cEBSCO|tebscoebooksacademic|lridw 
994    92|bRID