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BestsellerE-book

Title Cancer drug design and discovery / edited by Stephen Neidle.

Publication Info. New York : Academic Press, [2008]
©2008

Item Status

Edition 1st ed.
Description 1 online resource (xv, 473 pages, 27 unnumbered pages of plates) : illustrations (some color)
Physical Medium polychrome
Description text file
Bibliography Includes bibliographical references and index.
Contents Modern cancer drug discovery : integrating targets, technologies and treatments / Paul Workman and Ian Collins -- Preclinical pharmacology and in vivo models / Lloyd Kelland -- Clinical trial designs for more rapid proof-of-principle and approval / Mitesh J. Borad and Daniel D. Van Hoff -- Structural biology and anticancer drug design / Dominic Tisi [and others] -- Natural product chemistry and anticancer drug discovery / Donna M. Huryn and Peter Wipf -- Pharmacokinetics and ADME optimization in drug discovery / Chad L. Stoner, Matthew D. Troutman and Caroline E. Laverty -- Temozolomide : from cytotoxic to molecularly-targeted agent / Malcolm F.G. Stevens -- Camptothecins for drug design, cancer cell death and gene targeting / Jérôme Kluza [and others] -- Targeting thymidylate synthase by antifolate drugs for the treatment of cancer / Ann L. Jackman, Martin Forster and Matthew Ng -- Targeting inactive kinases : structure as a foundation for cancer drug discovery / David J. Hosfield and Clifford D. Mol -- Cell cycle inhibitors in cancer : current status and future directions / Peter M. Fischer -- Inhibition of DNA repair as a therapeutic target / Nicola J. Curtin and Thomas Helleday -- HSP90 inhibitors : targeting the cancer chaperone for combinatorial blockade of oncogenic pathways / Swee Y. Sharp, Keith Jones and Paul Workman -- Heat shock protein-90 directed therapeutics and target validation / Edward A. Sausville -- Inhibitors of tumor angiogenesis / Adrian L. Harris and Daniele G. Generali -- The biology and oncology of RAF-ERK signaling / Victoria Emuss and Richard Marais -- Cancer drug resistance / V. Karavasilis [and others] -- Failure modes in anticancer drug discovery and development / Homer L. Pearce, Kerry L. Blanchard and Christopher A. Slapak.
Local Note eBooks on EBSCOhost EBSCO eBook Subscription Academic Collection - North America
Subject Antineoplastic agents -- Development.
Antineoplastic agents -- Development.
Antineoplastic agents -- Design.
Antineoplastic agents -- Design.
Antineoplastic agents.
Cancer -- Chemotherapy.
Cancer -- Chemotherapy.
Antineoplastic Agents.
Drug Design.
Neoplasms -- drug therapy.
Genre/Form Electronic books.
Added Author Neidle, Stephen, editor.
Other Form: Print version: Cancer drug design and discovery. 1st ed. New York : Academic Press, ©2008 9780123694485 0123694485 (OCoLC)154760280
ISBN 9780080554952 (electronic book)
0080554954 (electronic book)
9780123694485
0123694485