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BestsellerE-book
Author Clausen, Torben, author.

Title The Na+, K+ pumps keep us going : how passive and active transport of sodium (Na+) and potassium (K+) control performance and fatigue in skeletal muscle / by Torben Clausen.

Publication Info. Aarhus, Denmark : Aarhus University Press, 2016.

Item Status

Description 1 online resource (120 pages) : illustrations (some color), charts (some color
text file
Bibliography Includes bibliographical references (pages 107-120)
Contents The Na+, K+ pump and its discovery -- The transport and distribution of Na+ and K+ in skeletal muscle and how they are quantified -- Rapid passive fluxes of Na+ and K+ start muscle contraction and set a limit to excitability -- The definition, structure and function of the Na+, K+-pump -- The synthesis and localization of the Na+, K+ pumps in skeletal muscle -- Measurements of the content of [3H]ouabain binding sites indicate that in skeletal muscle, the major part of these binding sites of the Na+, K+ pumps are localized on the outer surface of sarcolemma and in the t-tubules -- The content of Na+, K+ pumps in skeletal muscles and how it can be quantified -- Muscle contractions, Na+, K+ transport and sodium potassium fatigue -- The rate of [³H]ouabain binding to sarcolemma can be quantified and what information may this provide? -- Measurements of [3H]ouabain binding to other cell types and preparations -- Acute and long-term regulation of Na+, K+ pumps in skeletal muscle -- Catecholamines and caffeine -- Peptide hormones stimulating the Na+, K+ pumps -- Insulin-like growth Factore-I (IGF-I) -- CGRP and other calcitonins -- Amylin, related peptides, and other stimuli for the Na+, K+ -pumps -- The importance of Na+-influx in causing depolarization and muscle fatigue -- Effect of varying Na+, K+-pump stimulating agents on intracellular Na+ in rat soleus muscles and how this may compensate functional defects caused by plasma membrane leakage -- Long-Term regulation of Na+, K+ pump content -- Training, inactivity and denervation -- Muscular dystrophy and McArdle disease -- Hyperkalemic periodic paralysis in horses, human subjects and mutant mice with a similar geneti anomaly -- K+ deficiency and K+ restoration -- Thyroid hormones ans starvation -- Thermogenic actions of thyroid hormones and malignant hyperthermia (MH) -- Diabetes -- Steroid hormones, glucocorticoids, aldosterone -- Major conclusions and general perspectives.
Local Note eBooks on EBSCOhost EBSCO eBook Subscription Academic Collection - North America
Subject Sodium/potassium ATPase.
Sodium/potassium ATPase.
Sodium -- Physiological transport.
Sodium -- Physiological transport.
Potassium -- Physiological transport.
Potassium -- Physiological transport.
Potassium.
Genre/Form Electronic books.
Added Author ProQuest (Firm)
Other Form: Print version: 8771249397 9788771249392
ISBN 9788771842470 (electronic bk)
8771842470 (electronic bk)
8771249397
9788771249392