LEADER 00000cam a2200685Ia 4500 001 ocn154725799 003 OCoLC 005 20160527040514.5 006 m o d 007 cr cnu---unuuu 008 070712s2006 ne a obf 001 0 eng d 019 162569555|a505089651|a648303394 020 9780080491400|q(electronic book) 020 0080491405|q(electronic book) 020 9780120883875 020 0120883872 020 |z0120883872|q(alkaline paper) 035 (OCoLC)154725799|z(OCoLC)162569555|z(OCoLC)505089651 |z(OCoLC)648303394 037 106123:106154|bElsevier Science & Technology|nhttp:// www.sciencedirect.com 040 N$T|beng|epn|cN$T|dOCLCQ|dYDXCP|dOCLCQ|dUBY|dE7B|dOCLCQ |dDEBBG|dREDDC|dOCLCQ|dOCLCO|dOCLCQ|dOCLCF|dNLGGC|dOCLCO |dOCLCQ|dOCL|dOPELS|dOCLCQ 049 RIDW 050 4 QP86|b.H35 2006eb 072 7 MED|x058060|2bisacsh 072 7 FAM|x005000|2bisacsh 082 04 612.6/7|222 090 QP86|b.H35 2006eb 245 00 Handbook of the biology of aging /|ceditors, Edward J. Masoro and Steven N. Austad. 246 30 Biology of aging 250 6th ed. 264 1 Amsterdam ;|aBoston :|bElsevier Academic Press,|c[2006] 264 4 |c©2006 300 1 online resource (xx, 660 pages) :|billustrations. 336 text|btxt|2rdacontent 337 computer|bc|2rdamedia 338 online resource|bcr|2rdacarrier 340 |gpolychrome|2rdacc 347 text file|2rdaft 490 1 The handbooks of aging 504 Includes bibliographical references and indexes. 505 0 Section I. Conceptual and technical issues. Reliability theory of aging and longevity / Leonid A. Gavrilov and Natalia S. Gavrilova -- Are age-associated diseases an integral part of aging? / Edward J. Masoro -- Dietary restriction, hormesis, and small molecule mimetics / David A. Sinclair and Konrad T. Howitz -- Hematopoietic stem cells, aging, and cancer / Deborah R. Bell and Gary Van Zant -- Mitochondria: a critical role in aging / Tamara R. Golden [and others] -- P53 and mouse aging models / Catherine Gatza [and others] -- Complex genetic architecture of Drosophila longevity / Trudy F.C. Mackay [and others] -- Evolutionary biology of aging: future directions / Daniel E.L. Promislow, Kenneth M. Fedorka, and Joep M.S. Burger -- Senescence in wild populations of mammals and birds / Anja K. Brunet-Rossinni and Steven N. Austad -- Biodemography of aging and age-specific mortality in Drosophila melanogaster / James W. Curtsinger, Natalia S. Gavrilova, and Leonid A. Gavrilov -- Microarray analysis of gene expression changes in aging / F. Noel Hudson [and others] -- Computer modeling in the study of aging / Thomas B.L. Kirkwood [and others] -- Section II. Non-mammalian models. Dissecting the processes of aging using the nematode Caenorhabditis elegans / Samuel T. Henderson, Shane L. Rea, and Thomas E. Johnson -- Genetic manipulation of life span in Drosophila melanogaster / Daniel Ford and John Tower -- Juvenile and steroid hormones in Drosophila melanogaster longevity / Meng-Ping Tu, Thomas Flatt, and Marc Tatar -- A critical evaluation of nonmammalian models for aging research / Steven N. Austad and Andrei Podlutsky -- Section III. Mammalian models. Differential aging among skeletal muscles / Roger J.M. McCarter -- Aging, body fat, and carbohydrate metabolism / Marielisa Rincon, Radhika Muzumdar, and Nir Barzilai -- Growth and aging: why do big dogs die young? / Richard A. Miller and Steven N. Austad -- Growth hormone, insulin-like growth factor-1, and the biology of aging / Christy S. Carter and William E. Sonntag -- Aging of the female reproductive system / Phyllis M. Wise. 520 The Handbook of the Biology of Aging, Sixth Edition, provides a comprehensive overview of the latest research findings in the biology of aging. Intended as a summary for researchers, it is also adopted as a high level textbook for graduate and upper level undergraduate courses. The Sixth Edition is 20% larger than the Fifth Edition, with 21 chapters summarizing the latest findings in research on the biology of aging. The content of the work is virtually 100% new. Though a selected few topics are similar to the Fifth Edition, these chapters are authored by new contributors with new information. The majority of the chapters are completely new in both content and authorship. The Sixth Edition places greater emphasis and coverage on competing and complementary theories of aging, broadening the discussion of conceptual issues. Greater coverage of techniques used to study biological issues of aging include computer modeling, gene profiling, and demographic analyses. Coverage of research on Drosophilia is expanded from one chapter to four. New chapters on mammalian models discuss aging in relation to skeletal muscles, body fat and carbohydrate metabolism, growth hormone, and the human female reproductive system. Additional new chapters summarize exciting research on stem cells and cancer, dietary restriction, and whether age related diseases are an integral part of aging. The Handbook of the Biology of Aging, Sixth Edition is part of the Handbooks on Aging series, including Handbook of the Psychology of Aging and Handbook of Aging and the Social Sciences, also in their 6th editions. 588 0 Print version record. 590 eBooks on EBSCOhost|bEBSCO eBook Subscription Academic Collection - North America 650 0 Aging|xPhysiological aspects|0https://id.loc.gov/ authorities/subjects/sh2007100674|vHandbooks, manuals, etc.|0https://id.loc.gov/authorities/subjects/sh99001300 650 2 Aging|xphysiology.|0https://id.nlm.nih.gov/mesh/ D000375Q000502 650 7 Aging|xPhysiological aspects.|2fast|0https:// id.worldcat.org/fast/800323 655 4 Electronic books. 655 7 Handbooks and manuals.|2fast|0https://id.worldcat.org/fast /1423877 655 7 Handbooks and manuals.|2lcgft|0https://id.loc.gov/ authorities/genreForms/gf2014026109 700 1 Masoro, Edward J.|0https://id.loc.gov/authorities/names/ n80090418 700 1 Austad, Steven N.,|d1946-|0https://id.loc.gov/authorities/ names/n97007177 776 08 |iPrint version:|tHandbook of the biology of aging.|b6th ed.|dAmsterdam ; Boston : Elsevier Academic Press, ©2006 |z0120883872|z9780120883875|w(DLC) 2005023985 |w(OCoLC)61453894 830 0 Handbooks of aging.|0https://id.loc.gov/authorities/names/ n84744657 856 40 |uhttps://rider.idm.oclc.org/login?url=http:// search.ebscohost.com/login.aspx?direct=true&scope=site& db=nlebk&AN=194963|zOnline eBook. Access restricted to current Rider University students, faculty, and staff. 856 42 |3Instructions for reading/downloading this eBook|uhttp:// guides.rider.edu/ebooks/ebsco 901 MARCIVE 20231220 948 |d20160615|cEBSCO|tebscoebooksacademic|lridw 994 92|bRID